Jounce Therapeutics

  • Medical Director/Senior Medical Director

    Job ID
    Medical Affairs
    Job Location
  • Company Summary

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long lasting benefits to patients. Through the use of its Translational Science Platform, Jounce first focuses on specific cell types within the human tumor microenvironment (TME) to prioritize targets, and then identifies related biomarkers designed to match the right immunotherapy to the right patient. Jounce has three development stage programs: its two clinical product candidates, JTX-2011, a monoclonal antibody that binds to and activates ICOS, and JTX-4014, a monoclonal antibody that binds to PD-1 to be used in combination with its pipeline of future product candidates, and JTX-8064, a monoclonal antibody that binds to Leukocyte Immunoglobulin Like Receptor B2 (LILRB2) that is currently in the IND-enabling phase. For more information, please visit



    Role / Responsibilities

    The Medical Director will design and execute clinical development strategy for Jounce’s lead Macrophage program candidate.  He or she will be responsible for all clinical activities related to the program.  He or she will also work with the Business Development team to assess external compounds for potential addition to the Jounce portfolio.  As Jounce grows and brings new drugs into the clinic, there will be an opportunity to take on more responsibility and play an important leadership role in the company.


    • Participate in IND preparation
    • Protocol development
    • Study implementation
    • Medical Monitoring
    • Safety oversight
    • Primary contact with study investigators
    • Study enrollment
    • Data analysis and interpretation and primary author of clinical study reports
    • Clinical support to clinical operations, regulatory, research, and manufacturing functions
    • Clinical representative on Product Team and other cross-functional teams




    • MD with at least 5 years of pharmaceutical or biotechnology industry experience in oncology clinical development OR academic clinical research; experience in early phase and in immuno-oncology preferred.
    • Board certified in internal medicine and medical oncology
    • In depth knowledge and experience with Good Clinical Practice

    Preferred Skills:

    • Experience designing, conducting, serving as medical monitor, and analyzing data in Phase 1-2 clinical trials in oncology.
    • Strong Scientific/ Translational experience
    • Experience interacting with Contract Research Organizations
    • Prior experience writing and submitting INDs to FDA; experience with pre-IND and EOP1 meetings preferred.
    • Ability to work in a high paced team environment, meet deadlines, & prioritize work on multiple projects
    • Strong verbal and written skills
    • History of strong relationships with academic investigators

    To apply, please visit



    Jounce Therapeutics is an equal opportunity employer and does not discriminate in it’s employment decisions on the basis of race, color, national origin, age, physical or mental disability, marital status, religion, creed, sex, or political beliefs.  We offer a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the U.S.



    To apply, please visit


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