• Lead Scientist, Bioanalytical Assays

    Job ID
    2018-1141
    Category
    Operations
    Job Location
    US-MA-Cambridge
  • Company Summary

    Jounce Therapeutics, Inc. is a clinical stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long‑lasting benefits to patients. Through the use of its Translational Science Platform, Jounce first focuses on specific cell types within tumors to prioritize targets, and then identifies related biomarkers designed to match the right therapy to the right patient. Jounce’s lead product candidate, JTX-2011, is a monoclonal antibody that binds to and activates ICOS and is currently in the Phase 2 portion of the Phase 1/2 ICONIC trial. For more information, please visit www.jouncetx.com.

    Role / Responsibilities

    We are seeking an individual with expertise in bioanalytical assays and experience managing (or working within) CROs to deliver GLP and clinical assays. The candidate will possess deep scientific and technical knowledge and experience in developing, transferring, optimizing and validating assays to support pre-clinical and clinical development of biologics programs. You will be responsible for external work at CROs from strategy, SOW development, timely execution of laboratory work and report writing and review. In this role you will provide expert technical guidance to internal and external teams. You will operate independently and oversee the external development and validation of assays for pharmacokinetics, anti-drug antibodies and neutralizing antibodies assays in a regulated environment. Oversee screening operations, including scheduling, assay performance and data flow. Provide expert review of clinical data generated with these assays.  A key component of this role is to manage relationships with CROs and ensure they are delivering high quality data in a timely fashion and in compliance with regulatory standards.  The ideal candidate will be collaborative with the ability to work cross-functionally, to effectively communicate with key stakeholders, and to participate on program teams.

    Qualifications

    Extensive industry experience in development and assessment of GLP bioanalytical assays related to biologics.

    Life science degree required – PhD with 5+ years of experience or BS/MS with 10+ years of experience.

    Technical expertise in bioanalytical assay development, optimization, and validation for biologics. Hands-on experience with assay development is highly desirable.

    Experience managing outsourced bioanalytical activities at CROs, or experience working within a CRO.

    Experience working in a regulated environment.

    Strong organizational skills with attention to details, budget and timelines.

    Excellent verbal and written communication skills including technical writing skills.

    Ability to thrive in a highly collaborative, fast-paced, team-oriented environment.

     

    To apply, please visit https://careers-jouncetx.icims.com/.

    Statement

    Jounce Therapeutics is an equal opportunity employer and does not discriminate in it’s employment decisions on the basis of race, color, national origin, age, physical or mental disability, marital status, religion, creed, sex, or political beliefs. 

     

    We offer a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the U.S.

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