• Contractor, Preclinical Sciences Group

    Job ID
    Research & Development
    Job Location
  • Company Summary

    Jounce Therapeutics, Inc. is a clinical stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long‑lasting benefits to patients. Through the use of its Translational Science Platform, Jounce first focuses on specific cell types within tumors to prioritize targets, and then identifies related biomarkers designed to match the right therapy to the right patient. Jounce’s lead product candidate, JTX-2011, is a monoclonal antibody that binds to and activates ICOS and is currently in the Phase 2 portion of the Phase 1/2 ICONIC trial. For more information, please visit www.jouncetx.com.

    Role / Responsibilities

    We are looking for a creative and highly motivated research associate to join the Preclinical Sciences group at Jounce Therapeutics.  The successful candidate will be an integral part of a team of scientists supporting the preclinical and clinical development of novel cancer biologics.  Primary responsibilities include designing and developing cell-based, mechanistic assays to support preclinical research and clinical development.  You will be responsible for the proper design and execution of experiments, data analysis and interpretation, thorough documentation of work, and clear communication of results both in group settings and in written reports. In this role you will work across R&D functions and interact with a diverse group of scientists. 




    • Development and execution of immunological assays, using both primary cells as well as common cell lines, to support development of novel immunotherapies
    • Thorough documentation of experiments and communication of results across functional teams.
    • Drafting documents in support of regulatory filings.



    • S. or M.S. with 0-2 years of relevant laboratory experience in immunology or related field, with industrial experience a plus.
    • Experience and comfort with the isolation of immune cells from blood and tissue, testing therapeutics in cellular assays, and phenotyping of immune cells.
    • Extensive hands-on experience with immunological techniques including multi-parameter flow cytometry, single-cell sorting, and in vitro functional assays including CD4 proliferation assays as well as cytotoxicity assays.
    • Able to work with tissues and blood products.
    • Proficient at independently designing and executing experiments, analyzing data, and reporting conclusions to team members.
    • Excellent organizational and time management skills.
    • Able to thrive in a highly collaborative, fast-paced, team-oriented environment

    To apply, please visit https://careers-jouncetx.icims.com/


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