Sr. Program Executive – Immuno-oncology

Job ID
Clinical Development

Company Summary

Jounce Therapeutics, Inc. (JNCE) is a clinical stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long‑lasting benefits to patients. Through the use of its Translational Science Platform, Jounce first focuses on specific cell types within tumors to prioritize targets, and then identifies related biomarkers designed to match the right therapy to the right patient. Jounce’s lead product candidate, JTX-2011, is a monoclonal antibody that binds to and activates ICOS and is currently in a Phase 1/2 trial. 

Role / Responsibilities

Reporting directly to the Chief Medical Officer, in this role you will lead the team(s) responsible for the development and implementation of the scientific and clinical strategy and plans for key Jounce programs  as they transition from the preclinical to clinical stage, working in close partnership with a senior program manager.  The successful candidate will have a proven track record in effectively leading biologics drug development teams as well as a strong scientific and/or clinical background preferably in immuno-oncology or a closely related therapeutic area.


  • Develop the overall program vision including scientific, clinical, and pre-commercial strategies and plans through BLA and commercialization
  • Lead the strategic planning, decision-making, and risk assessment processes to deliver quality outcomes
  • Ensures rigorous scientific debate and robust data quality through effectively gathering team, subject matter, and cross functional feedback
  • Possess a basic understanding of all functions represented on the team in order to ask probing questions and assess risk  
  • Ensure cross-functional alignment within the project team and with corporate/Management Team strategy, proactively communicate throughout all phases of program strategy and execution
  • Hold team accountable for deliverables and timelines; instill appropriate sense of urgency
  • Hold decision rights and advance program to its next agreed upon milestones through data-driven decisions
  • Work creatively to find solutions to problems and overcome obstacles
  • Manage all aspects of program timelines and deliverables, anticipate risks and proactively communicate potential impacts and mitigation plans to the Management Team
  • Represent the program to executive stakeholders including the Board of Directors
  • Contribute to the building of a strong alliance; ensure the program(s) fulfill their partnership responsibilities and effectively communicate with the joint committees
  • Foster a fun environment; mentor and develop a cross-functional team, create excitement and affiliation, sustain morale when tough times arise


  • PhD, MD or equivalent in Immunology, Oncology or related field
  • 10+ years industry experience in Oncology, Immunology or preferably Immuno-oncology with demonstrated expertise in biologics drug development
  • Proven track record of leading, coaching and developing high functioning teams to drive programs through preclinical to clinical stage
  • Strong program/project management skills
  • Strong relationship building, leadership, and communication skills required
  • Facilitator for efficient decision making and mediation of conflict resolution
  • Skilled at understanding team dynamics, ability to leverage strengths and mitigate weaknesses 

To apply, please visit 


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